Veröffentlichungen von
Veröffentlichungen
Prof. Dr. Jost Seibler
Kapitel in einem Sammelwerk
Transgenic RNAi Applications in the Mouse
Seibler, Jost ; Schwenk, Frieder (2010)
Methods in Enzymology : Guide to Techniques in Mouse Development, Part B: Mouse Molecular Genetics. 2nd Edition. Amsterdam : Elsevier 2010. Seite: 367 - 386
978-0-12-384880-2
Zeitschriftenartikel
Generation and utility of genetically humanized mouse models
Scheer, Nico ; Snaith, Mike ; Wolf, C. Roland ; Seibler, Jost (2013)
Drug Discovery Today. Amsterdam : Elsevier. Vol 18 (2013), H. 23-24. Seite: 1200 - 1211
1359-6446
A High-Throughput Functional Complementation Assay for Classification of BRCA1 Missense Variants
Bouwman, Peter ; Gulden, Hanneke van der ; Heijden, Ingrid van der ; Drost, Rinske ; Klijn, Christiaan N. ; Prasetyanti, Pramudita ; Pieterse, Mark ; Wientjens, Ellen ; Seibler, Jost ; Hogervorst, Frank B. L. ; Jonkers, Jos (2013)
Cancer Discovery. . (2013), H. 3. Seite: 1142 - 1152
2159-8290
Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool
Michalak, Ewa Malgorzata ; Nacerddine, Karim ; Pietersen, Alexandra ; Beuger, Vincent ; Pawlitzky, Inka ; Cornelissen-Steijger, Paulien ; Wientjens, Ellen ; Tanger, Ellen ; Seibler, Jost ; Lohuizen, Maarten van ; Jonkers, Jos (2013)
Stem Cells. Oxford : Oxford University Press. Vol 31 (2013), H. 9. Seite: 1910 - 1920
1549-4918
Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1
Gebeshuber, Christoph A. ; Kornauth, Christoph ; Dong, Lihua ; Sierig, Ralph ; Seibler, Jost ; Reiss, Martina ; Tauber, Stefanie ; Bilban, Martin ; Wang, Shijun ; Kain, Renate ; Böhmig, Georg A. ; Moeller, Marcus J. ; Gröne, Hermann-Josef ; Englert, Christoph ; Martinez, Javier ; Kerjaschki, Dontscho (2013)
Nature Medicine. . 19 (2013), H. 4. Seite: 481 - 487
1078-8956
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
Kornfeld, Jan-Wilhelm ; Baitzel, Catherina ; Könner, A. Christine ; Nicholls, Hayley T. ; Vogt, Merly C. ; Herrmanns, Karolin ; Scheja, Ludger ; Haumaitre, Cécile ; Wolf, Anna M. ; Knippschild, Uwe ; Seibler, Jost ; Cereghini, Silvia ; Heeren, Joerg ; Stoffel, Markus ; Brüning, Jens C. (2013)
Nature. Cham : Springer Nature. 494 (2013), H. 7435. Seite: 111 - 115
0028-0836
Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells
Raab, Monika ; Kappel, Sven ; Krämer, Andrea ; Sanhaji, Mourad ; Matthess, Yves ; Kurunci-Csacsko, Elisabeth ; Calzada-Wack, Julia ; Rathkolb, Birgit ; Rosman, Jan ; Adler, Thure ; Busch, Dirk H. ; Esposito, Irene ; Fuchs, Helmut ; Gailus-Durner, Valérie ; Klingenspor, Martin ; Wolf, Eckhard ; Sänger, Nicole ; Prinz, Florian ; Hrabe de Angelis, Martin ; Seibler, Jost ; Yuan, Juping ; Bergmann, Martin ; Knecht, Rainald ; Kreft, Bertolt ; Strebhardt, Klaus (2011)
Nature Communications. London : Nature. 2 (2011), H. 395. Seite: 1 - 11
2041-1723
Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line
Hasegawa, Maki ; Kapelyukh, Yury ; Tahara, Harunobu ; Seibler, Jost ; Rode, Anja ; Krueger, Sylvia ; Lee, Dongtao N. ; Wolf, C. Roland ; Scheer, Nico (2011)
Molecular Pharmacology. Bethesda, Md. : ASPET. 80 (2011), H. 33. Seite: 518 - 528
1521-0111
Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
Jordan, Sabine D. ; Krüger, Markus ; Willmes, Diana M. ; Redemann, Nora ; Wunderlich, F. Thomas ; Brönneke, Hella S. ; Merkwirth, Carsten ; Kashkar, Hamid ; Olkkonen, Vesa M. ; Böttger, Thomas ; Braun, Thomas ; Seibler, Jost ; Brüning, Jens C. (2011)
Nature Cell Biology. New York : Nature. 13 (2011), H. 4. Seite: 434 - 446
1465-7392
Meiotic functions of RAD18
Inagaki, Akiko ; Sleddens-Linkels, Esther ; Wassenaar, Evelyne ; Ooms, Marja ; Cappellen, Wiggert A. van ; Hoeijmakers, Jan H. J. ; Seibler, Jost ; Vogt, Thomas F. ; Shin, Myung K. ; Grootegoed, J. Anton ; Baarends, Willy M. (2011)
Journal of Cell Science. Cambridge : Company of Biologists Limited. 124 (2011), H. 16. Seite: 2837 - 2850
1477-9137
The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis
Glaser, Stefan ; Lubitz, Sandra ; Loveland, Kate L. ; Ohbo, Kazu ; Robb, Lorraine ; Schwenk, Frieder ; Seibler, Jost ; Roellig, Daniela ; Kranz, Andrea ; Anastassiadis, Konstantinos ; Stewart, A. Francis (2009)
Epigenetics & Chromatin. . 2 (2009), H. 5. Seite: 1 - 16
1756-8935
Inducible transgenic rat model for diabetes mellitus based on shRNA-mediated gene knockdown
Kotnik, Katarina ; Popova, Elena ; Todiras, Mihail ; Mori, Marcelo A. ; Alenina, Natalia ; Seibler, Jost ; Bader, Michael (2009)
Plos One. San Francisco, California, US : Plos. 4 (2009), H. 4. Seite: e5124
Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats
Herold, Marco J. ; Brandt, Jens van den ; Seibler, Jost ; Reichardt, Holger M. (2008)
Proceedings of the National Academy of Sciences of the United States of America. . 105 (2008), H. 47. Seite: 18507 - 18512
1091-6490
Central insulin action regulates peripheral glucose and fat metabolism in mice
Koch, Linda ; Wunderlich, F. Thomas ; Seibler, Jost ; Könner, A. Christine ; Hampel, Brigitte ; Irlenbusch, Sigrid ; Brabant, Georg ; Kahn, C. Ronald ; Schwenk, Frieder ; Brüning, Jens C. (2008)
The Journal of Clinical Investigation (JCI). . 118 (2008), H. 6. Seite: 2132 - 2147
1558-8238
Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice
Christoph, Thomas ; Bahrenberg, Gregor ; Vry, Jean de ; Englberger, Werner ; Erdmann, Volker A. ; Frech, Moritz ; Kögel, Babette ; Röhl, Thomas ; Schiene, Klaus ; Schröder, Wolfgang ; Seibler, Jost ; Kurreck, Jens (2008)
Molecular and Cellular Neuroscience. . 37 (2008), H. 3. Seite: 579 - 589
1044-7431
Reversible gene knockdown in mice using a tight, inducible shRNA expression system
Seibler, Jost ; Kleinridders, Andre ; Küter-Luks, Birgit ; Niehaves, Sandra ; Brüning, Jens C. ; Schwenk, Frieder (2007)
Nucleic Acids Research. . 35 (2007), H. 7. Seite: e54
1362-4962
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity
Plum, Leona ; Ma, Xiaosong ; Hampel, Brigitte ; Balthasar, Nina ; Coppari, Roberto ; Münzberg, Heike ; Shanabrough, Marya ; Burdakov, Denis ; Rother, Eva ; Janoschek, Ruth ; Alber, Jens ; Belgardt, Bengt F. ; Koch, Linda ; Seibler, Jost ; Schenk, Frieder ; Fekete, Csaba ; Suzuki, Akira ; Mak, Tak W. ; Krone, Wilhelm ; Horvath, Tamas L. ; Ashcroft, Frances M. ; Brüning, Jens C. (2006)
The Journal of Clinical Investigation (JCI). . 116 (2006), H. 7. Seite: 1886 - 1901
1558-8238
Single copy shRNA configuration for ubiquitous gene knockdown in mice
Seibler, Jost ; Küter-Luks, Birgit ; Kern, Heidrun ; Streu, Sandra ; Plum, Leona ; Maurer, Jan ; Kühn, Ralf ; Brüning, Jens C. ; Schwenk, Frieder (2005)
Nucleic Acids Research. . 33 (2005), H. 7. Seite: e67
1362-4962
Performance of genomic bordering elements at predefined genomic loci
Goetze, Sandra ; Baer, Alexandra ; Winkelmann, Silke ; Nehlsen, Kristina ; Seibler, Jost ; Maass, Karin ; Bode, Jürgen (2005)
Molecular and Cellular Biology. . 25 (2005), H. 6. Seite: 2260 - 2272
1098-5549
Elk-1 knock-out mice engineered by Flp recombinase-mediated cassette exchange
Cesari, Francesca ; Rennekampff, Verena ; Vintersten, Kristina ; Vuong, Lam Giang ; Seibler, Jost ; Bode, Jürgen ; Wiebel, Franziska F. ; Nordheim, Alfred (2004)
Genesis : The Journal of Genetics and Development. . 38 (2004), H. 2. Seite: 87 - 92
1526-968X
Rapid generation of inducible mouse mutants
Seibler, Jost ; Zevnik, Branko ; Küter-Luks, Birgit ; Andreas, Susanne ; Kern, Heidrun ; Hennek, Thomas ; Rode, Anja ; Heimann, Cornelia ; Faust, Nicole ; Kauselmann, Gunther ; Schoor, Michael ; Jaenisch, Rudolf ; Rajewsky, Klaus ; Kühn, Ralf ; Schwenk, Frieder (2003)
Nucleic Acids Research. . 33 (2003), H. 4. Seite: e12
1362-4962
The transgeneticist's toolbox: novel methods for the targeted modification of eukaryotic genomes
Bode, Jürgen ; Schlake, Thomas ; Iber, Michaela ; Schübeler, Dirk ; Seibler, Jost ; Snezhkov, Evgeney ; Nikolaev, Lev (2000)
Biological Chemistry. . 381 (2000), H. 9-10. Seite: 801 - 813
1431-6730
Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange
Feng, Yong-Qing ; Seibler, Jost ; Alami, Raouf ; Eisen, Andrew ; Westerman, Karen A. ; Leboulch, Philippe ; Fiering, Steven ; Bouhassira, Eric E. (1999)
Journal of Molecular Biology. . 292 (1999), H. 4. Seite: 779 - 785
0022-2836
DNA cassette exchange in ES cells mediated by Flp recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs
Seibler, Jost ; Schübeler, Dirk ; Fiering, Steven ; Groudine, Mark ; Bode, Jürgen (1998)
Biochemistry. . 37 (1998), H. 18. Seite: 6229 - 6234
1520-4995
Transcription-promoting genomic sites in mammalia: their elucidation and architectural principles
Bode, J. ; Bartsch, J. ; Boulikas, T. ; Iber, M. ; Mielke, C. ; Schübeler, D. ; Seibler, Jost ; Benham, C. (1998)
Gene therapy & molecular biology. . 1 (1998), H. 1. Seite: 1 - 29
1529-9120
Efficient FACS selection procedure for cells undergoing Flp-mediated site-specific conversions
Iber, Michaela ; Schübeler, Dirk ; Seibler, Jost ; Höxter, Maria ; Bode, Jürgen (1998)
Technical Tips Online. . 4 (1998), H. 1. Seite: 25 - 29
Double-reciprocal crossover mediated by FLP-recombinase: a concept and an assay
Seibler, Jost ; Bode, Jürgen (1997)
Biochemistry. . 36 (1997), H. 7. Seite: 1740 - 1747
1520-4995